ENDOCYTIC MECHANISMS AND OSTEOINDUCTIVE PROFILE OF HYDROXYAPATITE NANOPARTICLES IN HUMAN UMBILICAL CORD WHARTON’S JELLY-DERIVED MESENCHYMAL STEM CELLS

Endocytic mechanisms and osteoinductive profile of hydroxyapatite nanoparticles in human umbilical cord Wharton’s jelly-derived mesenchymal stem cells

Xingxing Shi,* Kai Zhou,* Fei Huang,* Juan Zhang, Chen Wang Department of Prosthodontics, Jiangsu Key Laboratory of Oral Diseases, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China *These authors contributed equally to this work Background: As a potentially bioactive material, the widespread application of nanosized hyd

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Harnessing alkaline-pH regulatable promoters for efficient methanol-free expression of enzymes of industrial interest in Komagataella Phaffii

Abstract Background The yeast Komagataella phaffii has become a very popular host for heterologous protein expression, very often based on the use of the AOX1 promoter, which becomes activated when cells are grown with methanol as a carbon source.However, Laser Unit the use of methanol in industrial settings is not devoid of problems, and therefore

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Hypoxia-preconditioned WJ-MSC spheroid-derived exosomes delivering miR-210 for renal cell restoration in hypoxia-reoxygenation injury

Abstract Background Recent advancements in mesenchymal stem cell (MSC) technology have paved the way for innovative treatment options for various diseases.These stem cells play FPV Gear a crucial role in tissue regeneration and repair, releasing local anti-inflammatory and healing signals.However, challenges such as homing issues and tumorigenicity

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